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482 Patients who receive HD may be at risk of the development of carnitine deficiency as a result of loss of carnitine during the dialysis procedure, in addition to possible reductions in dietary intake and endogenous synthesis

Severe gastrointestinal disease: Caution is advised in patients with conditions such as gastroparesis or severe inflammatory bowel disease, as GLP-1 receptor agonism slows gastric emptying

Gaining 3 pounds of muscle while losing 3 pounds of fat shows zero change on the scale despite dramatic improvement in body composition

Currently, the only safe and legal way to access retatrutide is through a clinical trial like those listed on clinicaltrials.gov

Singh H, Sharma G

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