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While NRXN1 deletions are associated with impaired synaptic signaling and severe social communication deficits (Hu et al

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Phosphodiesterase-5 inhibitors such as sildenafil are generally safe to use alongside GLP-1 medications, though they are contraindicated with nitrates and should be used cautiously in certain cardiovascular conditions

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All injectable dosing protocols are extrapolations from the oral trial, animal data, and clinical practice experience