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Khavinson V.K., et al
AEs are more frequent in older adults compared to young adults, and they are particularly noted to occur during dose escalation [12, 43, 57, 75]
This brought with it new challenges both in terms of managing sexual partnerships as well as their health (Marks 2010)
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The three libraries were generated using error-prone PCR as described above, using the following conditions to produce varying levels of mutagenesis: Library 1: 30 M 8-oxo-dGTP, 1 M dPTP, 20 PCR cycles Library 2: 20 M 8-oxo-dGTP, 2 M dPTP, 20 PCR cycles Library 3: 10 M 8-oxo-dGTP, 3 M dPTP, 20 PCR cycles The library sizes (approximated by number of transformants as described above) were 6 10 7 for each library
