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PubMed Venkova, K., Mann, W., Nelson, R., & Greenwood-Van Meerveld, B
The most visually apparent sign is a change in cell size and shape
It plays a role in tissue regeneration, collagen production, and wound healing
Strikingly, this effect is mimicked by constitutively inhibiting endoplasmic Ca 2+ uptake with thapsigargin, or by stimulating phospholipase C (PLC), which both reduce ER Ca 2+ levels
Side Effects and Precautions Known Risks (Animal Studies + Anecdotal Reports) Potential for over-stimulation of neurogenesis , which is beneficial short-term but may carry unknown long-term risks Some users report: Mild headaches Irritability or emotional blunting Temporary insomnia if taken late in the day Theoretical Risk: Tumor Growth
These findings have led some to experiment with TB-500 for human use, hoping to reap similar benefits
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