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As an antioxidant present in cells throughout the body, glutathione helps neutralize free radicals and supports the body's detox pathways, which matters because oxidative stress is one of the forces that can accelerate collagen breakdown (Weschawalit et al., 2017)

We compared the differences in demographic and clinical characteristics between responders and non-responders using Chi-square tests and identified the significant predictors of nonresponse using logistic regression with stepwise selection

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That gap results in variable outcomes between trials and clinics