Two parallel pivotal Phase 3 trials extended the Phase 2 findings under controlled conditions across multi-centre populations, with the pooled analysis published in 2010 (PMID 20554713)
In another case report, two COVID-19 pneumonia patients were successfully treated with high doses of supplemental intravenous glutathione and oral NAC (Horowitz et al., 2020)
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It has been used as a supportive treatment in the management of certain liver diseases and in cancer therapy
Hameed A, Rehman TU, Rehan ZA, Noreen R, Iqbal S, Batool S, et al
In the future, it is necessary to develop more effective reversal therapies, optimize early diagnostic methods, and advance personalized treatment strategies to improve patient outcomes and quality of life