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Van Meter, 2005

Setting healthy expectations It helps to think about GLP1 weight loss in terms of percentages rather than specific pound targets

The connection between activation of IGF-1 receptors and endocrine regulation has also been researched

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Research from the New England Journal of Medicine documented that weight regain accelerates after GLP-1 discontinuation because the underlying metabolic conditions that led to weight gain remain unaddressed

Adipose tissue plays a role in oestrogen metabolism, and changes in body composition might temporarily influence the hypothalamic-pituitary-ovarian axis, though this remains speculative