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162 Pancreatic polypeptide is known to reduce pancreatic secretion to slow digestion but the effects on the rest of the GIT in humans are not currently clear

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Retatrutide represents a novel generation of research compounds in the anti-obesity and antidiabetic field, characterized by its unique mechanism of action involving the simultaneous activation of three metabolically relevant receptors: the GCG-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the GCG receptor (GCGR)

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Leyden J, Stein-Gold L, Weiss J

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