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The ATTAIN-1 trial reported a mean change in body weight at 72 weeks of -11.2% with the highest dose of orforglipron 36 mg compared to -2.1% with placebo in adults with obesity or overweight and at least one weight-related comorbidity
There was a 50% increase in Tom-20 in the SE offspring, although without statistical significance (Figure 7F)
The interesting piece here is specificity
doi: 10.1177/1179551420984130 226 KanamarlapudiVReedJBainS
J Invest Dermatol (2021) 141(4S):98592
thch L Tuyt Nhung mua ti rocy.vn c xp hng 5 5 sao Mnh th nhiu loi ri, thy loi ny d dng hn, khng b kh chu
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