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The Phase 3 TRIUMPH-4 trial (68 weeks) achieved average weight reductions of 28.7% at the 12 mg dose

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Objective To evaluate the efficacy and safety of intradermal injection of TXA, vitamin C, and glutathione under nerve block for melasma treatment

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In vitro , liraglutide dose-dependently downregulates pro-inflammatory mediators such as Mcp-1 and Cd38 in LPS-activated RAW264.7 macrophages, while simultaneously upregulating Erg-2, an M2-specific transcription factor (Yu et al., 2019)