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FOXO4-DRI functions as a competitive inhibitor, displacing p53 from FOXO4, thereby allowing the selective clearance of senescent cells (2, 9)

then, they treated the DM rats with intraperitoneal injection of exendin-4 at 1 nmol/kg for 24 weeks (49)

Studies have demonstrated that administration of isoniazid and rifampicin increases the abundance of Actinobacteria at the phylum level, as well as Bacteroides and Blautia at the genus level, while decreasing the abundance of Akkermansia [65, 66]

Some patients may experience gastrointestinal complications like gastroparesis or reflux, and rare risks include pancreatitis or low blood pressure

Medical supervision is essential because even low doses affect blood sugar, appetite, and hormone signaling