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Reasons for treatment discontinuation include, but are not limited to, gastrointestinal adverse effects, less-than-desired efficacy, high cost, and fear about uncommon or rare adverse effects
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This consistency is important for researchers doing long term studies or multi-phase research projects where compound variability can affect experimental outcome
In placebo-controlled trials, cholelithiasis was reported in 1.5% and 0.4% of patients treated with Semaglutide 0.5 mg and 1 mg, respectively, and not reported in placebo-treated patients
The committee weighed the evidence and the real world stakes and went the other way, six times
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