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In a 2025 study, bothersome hot flushes rose from 8.8% before menopause to 37.3% in late perimenopause

Patients using weekly semaglutide therapy should document each injection location in a calendar or app to eliminate guesswork and maintain systematic rotation that maximizes therapeutic benefit

This change goes through several stages

Many people prefer weekends so they can rest if nausea occurs

Renoprotective effects of combination treatment with sodium-glucose cotransporter inhibitors and GLP-1 receptor agonists in patients with type 2 diabetes mellitus according to preceding medication

doi: 10.1002/psc.2421 126 KerkisA.KerkisI.Radis-BaptistaG.OliveiraE