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These findings highlight CTP's potential as a functional food component that supports cardiovascular resilience, particularly in individuals at elevated risk of atherosclerosis [179, 183-185]
Don't expect a pure GIP/glucagon drug for human use anytime soon
The tissue-specific effect of l-carnitine was found in many experiments in mammals or fish, in which the carnitine content of muscle was relatively stable, whereas the liver was more sensitive to carnitine supplementation or deficiency ( Reference Li, Li and Qin 32 , Reference Morand, Bouitbir and Felser 48 , Reference Wchter, Vogt and Kreis 49 )
The cells were treated with metformin, and various cellular functions were assessed, including proliferation, apoptosis, migration, and epithelial-mesenchymal transition (EMT) status (68)
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2 Main TCMs as ferroptosis regulators in cancer 2.1 Terpenoids 2.1.1 Artemisinin and its derivatives 400 years ago, the famous Chinese herbalist Li Shi Zhen published in the Compendium of Materia Medica that fever and colds could be treated with qinghaosu preparations ( Artemisia annua by the Nobel laureate in Medicine and the Chinese scientist Tu Youyou in 1971, artemisinin has saved countless lives as an antimalarial drug ( Dihydroartemisinin (DHA), a derivative of artemisinin, can not only inhibit cell proliferation by inducing autophagy (Zou et al., 2019), but also exert its role by inhibiting the PRIM2/SLC7A11 axis and inducing ferroptosis (Yuan et al., 2020)
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