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10.3390/pharmaceutics16040505 26
It comes in a pre-filled pen that is easy to use
X: any amino acid) and is amenable to N-myristoylation (5, 6)
At 4 degrees Celsius (refrigerator temperature), hydrolysis proceeds slowly enough that the peptide retains the vast majority of its activity for 28 days
And these additives are very interesting
In some particular embodiments of the present invention, the coupling instep2 of the preparation method is performed by condensing with DIC+A or B+A+C until the resin is detected to be transparent with ninhydrin, wherein A is chosen from HOBt or HOAt, B is chosen from HBTU, HATU, TBTU, PyAOP, or PyBOP, C is chosen from DIPEA or TMP
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