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This chronic inflammation is a hallmark of aging and a fundamental link to various chronic diseases, including cardiovascular and neurodegenerative conditions

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For the treatment-regimen estimand, the mean body weight reductions from baseline at 72 weeks were 15.0%, 19.5%, and 20.9% in the tirzepatide 5, 10, and 15 mg groups, respectively, versus 3.1% in the placebo group

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