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Biochem J 320:100510, PMID: 9003392 Nikulina MA, Andersen HU, Karlsen AE, Darville MI, Eizirik DL, Mandrup-Poluson T (2000) Glutathione depletion inhibits interleukin 1 beta-stimulated nitric oxide production by reducing inducible nitric oxide synthase gene expression
While the choice can be like "splitting hairs," there are key differences in how they work
Findings are experimental and observational
Laboratory studies demonstrate that elimination of senescent cells through FOXO4-DRI administration can break the cycle of senescence induction and chronic inflammation, offering insights into interventions for age-related cellular dysfunction and tissue deterioration
Combination therapy with a dipeptidyl peptidase-4 inhibitor and a proton pump inhibitor induces -cell neogenesis from adult human pancreatic duct cells implanted in immunodeficient mice
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