Pay in 4 interest-free payments of $6.72 Learn more
Ships within 48 hours · Estimated delivery Sep 1 - Sep 6
TB-500 dosing less characterized Important: These are experimental doses used in animal studies and cannot be extrapolated to other species due to significant differences in metabolism, receptor density, pharmacokinetics, and peptide degradation rates
certificate of analysis available on request Research Applications Suitable Laboratory Uses for FOXO4-DRI FOXO4-p53 protein-protein interaction disruption assays CO-IP, competitive binding, and proximity ligation studies Selective senescent cell apoptosis induction SA--gal, p16, p21, p53 marker-confirmed senescent populations p53 TAD2 binding, phospho-p53 (Ser15) nuclear exclusion, and mitochondrial translocation pathway studies BAX/BCL-2/Caspase-3 intrinsic apoptosis cascade investigations in senescent cell models SASP characterisation and suppression IL-6, IL-8, MMP, VEGF, CXCL2/3 secretome studies Tissue-specific senescence models fibroblasts, endothelial cells, Leydig cells, chondrocytes, keloid fibroblasts Vascular ageing pathway research endothelial senescence, aortic function, and ROS pathway studies Senescent cancer cell biology and drug resistance pathway research Comparative senolytic research FOXO4-DRI vs
Store in a cool and dry place away from direct sunlight
Dramatic increase in fine lines or skin laxity
It stimulates lipolysis, which is the process of breaking down stored fat into fatty acids that the body can use for energy
A moisturizer containing ceramides can help maintain skin hydration and protect the skin barrier
