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Data availability This manuscript does not have data that need to be deposited in a public database

The dual role of COP1 as both an independent E3 ligase and a component of the CRL4 complex suggests that it may act as a molecular switch, toggling between distinct functional modes depending on cellular context

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Liposomal glutathione, for example, wraps the molecules in protective fat layers, helping them survive the journey through your digestive system

Topical use (soaps, lotions, creams) Lets focus especially on topical / skin-applied forms

Laser treatments and microneedling perhaps offer the best chances of eliminating visibility