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FOXO4-DRI also alleviated endothelial senescence induced by oxygen-glucose deprivation (OGD) in vitro, enhancing endothelial cell function
The animals were provided with ad libitum access to clean drinking water and a standard pellet diet
They are primarily used for antioxidant support, skin health improvement, reducing oxidative stress, and promoting overall wellness and immunity
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This synergistic effect potentially stems from ES-induced modulation of cell membrane permeability (CMP) that facilitates intracellular drug transport, coupled with enhanced drug action through cellular signaling pathway regulation (Zhao et al., 2020
It is important to mention that a core cell death machinery is evolutionarily conserved and is omnipresent in the majority of cellular types in multicellular organisms
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