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Ueda P, Svanstrm H, Melbye M et al (2018) Sodium glucose cotransporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study
H4K8la is enriched at promoters of meiotic genes and recombination hotspots, co-localizing with SPO11, DMC1, RAD51, and cohesin components (RAD21L, REC8), suggesting that lactylation serves as a metabolic cue coordinating gene activation and recombination during germ-cell meiosis [89]
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