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Recent data from the ATTAIN-MAINTAIN trial showed that patients transitioning to orforglipron after injectable GLP-1 therapy maintained their weight loss with minimal regain (approximately 0.9 kg after semaglutide transition), suggesting that oral maintenance strategies could minimize the lean mass depletion seen with prolonged high-dose injectable therapy
62 Fatty fish (like salmon, mackerel, and sardines), walnuts, and flaxseeds are rich in omega-3 fatty acids that may help protect and sustain glutathione levels by reducing oxidative stress
While taste alterations during treatment with GLP-1 receptor agonists or dual GIP/GLP-1 receptor agonists often improve over time as patients adjust to treatment, several strategies can help manage these changes and maintain adequate nutrition and quality of life
Increasing glutathione and its supporting enzymes has been shown to reduce oxidative damage and help remove toxic substances from the body
Plus, its often teamed up with favourites like Niacinamide, Hyaluronic Acid, or Kojic Acid for that extra oomph
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