In contrast to M1 macrophages, which primarily act during the early stages of osteoarthritis (OA), M2 macrophages exhibit anti-inflammatory properties and play a crucial role in promoting cartilage repair and regeneration (82) ( Figure 1 )
Its low molecular weight enables distribution throughout the bloodstream, reaching multiple tissues simultaneously
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BPC-157 can counteract the bleeding prolongation caused by certain medications, a potentially beneficial effect for some but concerning if anticoagulation is medically necessary
We cite them as published context, not independent proof
In addition, Met is regarded as an immunomodulatory agent and hence, plays a critical role in resisting microbial infection and diseases 11,13