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Skin-related complications of insulin therapy: epidemiology and emerging management strategies

These include: Nausea and vomiting (particularly during dose escalation) Diarrhoea or constipation Abdominal pain and bloating Reduced appetite Injection site reactions Headache These gastrointestinal symptoms typically improve over time as the body adjusts to the medication

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Perhaps most significantly, not a single serious adverse event was attributed to AOD-9604 administration across the entire trial program

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