However, the side effects associated with orlistat are not well tolerated and include flatulence, fecal urgency, and steatorrhea, restricting its use in the pediatric population
adults with type 1 diabetes
This disruption and subsequent infiltration of inflammatory mediators are associated with cognitive impairment in CKD patients, providing further evidence of a gut-brain connection (Sun et al., 2021)
Some people naturally have: Stronger GLP-1 responses they feel full on smaller portions Weaker GLP-1 responses they feel less satisfied and stay hungry longer When GLP-1 signals are weaker, a person may feel: Hungry again soon after meals Drawn to snacks even when they just ate Like it takes a lot of food to feel satisfied This is a big reason why weight control is not just about willpower. For many people, the problem starts with the signals, not their intentions
Cabungcal JH, Preissman D, Delseth C, Cunod M, Do KQ, Schenk F (2007)
Culprits include Diets high in REFINED carbs (carbs from whole foods dont cause blood sugar problems in healthy people, although people who already have metabolic issues may do better avoiding them) Chronic stress, which raises blood sugar