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To minimize side effects, our provider will adjust the gradual increase in your dose based on your weight loss goals and any side effects
Beyond that, a head-to-head comparison from the SURMOUNT-5 trial illustrates the difference clearly: Participants taking tirzepatide lost an average of 20.2% of their body weight compared to 13.7% with semaglutide
This is partly because the body's weight set point defends against the lower weight, and partly because GLP-1 receptors in the brain that were being continuously stimulated are no longer activated
Our guide on NHS weight loss injections has more information on the different treatments available and their costs
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Therefore, the efficacy and specific benefits of GLP-1RAs in HFpEF require further investigation
