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After reconstitution with bacteriostatic water, keep refrigerated at 28C and use within 30 days

If satisfactory clinical response has not been achieved, plasma levels should be measured to determine whether or not they are in the usually accepted therapeutic range (50-100 mcg/mL)

National Institutes of Health Office of Dietary Supplements 2021

Persistent or severe hypoglycemic episodes despite proper meal timing

The effectiveness of D-methionine in this connection brings back to mind the early studies of Rose who used DL-methionine in his early balance studies which led to the RDA recommendations, again suggesting a significant role for the SAA, beyond that of protein synthesis

For intramuscular injections, the common sites for B12 injections are the arm, upper buttocks, and thigh