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GLP-1 medications such as semaglutide and tirzepatide are well-studied and FDA-approved for weight management in eligible patients

Do not use Semaglutide if: You or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Clinical trials reveal that patients can experience a remarkable 15% to 20% body weight reduction, making it one of the most effective treatment options available today

Approximately 10% to 25% patients with NAFLD can progress to non-alcoholic steatohepatitis (NASH) and 10% to 15% patients with NASH develop hepatocellular carcinoma [2,3]

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If you fall into any of these groups, it is a good idea to have your B12 checked at baseline before starting tirzepatide and then periodically during treatment