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The formation and aggregation of these protein complexes mediated by lysosomal TM4SF5 highlight the biological importance of TM4SF5-enriched MLCS, which appear to play a crucial role in the mitochondrial dynamics, transfer of cholesterol from lysosomes to mitochondria and mitophagy in the context of extracellular glucose

The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cells

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Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis