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Thus, MT2 has been posited as an alternative for commonly used PDE5 inhibitors like sildenafil [13]

However, many treatments offer only temporary improvements, and no single treatment is universally effective for all patients

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Peer-reviewed research published in journals including the New England Journal of Medicine has demonstrated statistically significant weight loss outcomes with semaglutide and tirzepatide in large randomized controlled trials involving thousands of participants tracked over periods of 68 weeks or longer

If those factors are all optimized and the stall persists for 4 or more weeks, a dose increase may be appropriate

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