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Many patients experience a resurgence of hunger cues and food-related thoughts that had been diminished during treatment
It makes sense mechanistically, but the hard human clinical proof is limited
The improvements in erectile function correlated with hormonal improvements but also appeared to involve mechanisms independent of weight loss alone
If no meaningful weight loss or metabolic improvement is observed after 6 months of optimal therapy combined with lifestyle changes, clinicians may wish to discuss alternative approaches with the patient, though there is no formal UK guideline-mandated stopping rule for off-label metformin use in obesity
This data was unearthed as part of the Horizon 10 Report by Carbery Group, exploring GLP-1 usage and was further supplemented by a social listening exercise
This evaluation includes: Dr
