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Project Fund of China Medical University (No

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FoxO1 binds to the GPX 4 gene promoter, stimulating its expression and increasing the antioxidant capacity, thereby suppressing ferroptosis ( tuba3fp , which accelerates ubiquitin-dependent degradation of critical ferroptosis inducers such as IRGQ, further inhibiting ferroptosis ( Figure 2 ) ( 2.2.2 The role of the KRAS signaling pathway in cervical cancer cells resistance to ferroptosis Kirsten rat sarcoma viral oncogene (KRAS) is a member of the RAS gene family, located on the short arm of human chromosome 12 (12p1.1-pter)

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This interaction suppresses inflammation, contributes towards fibrinolysis (dissolving fibrin), and causes the release of protein C