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Xu H, Staszewski L, Tang H, Adler E, Zoller M, Li X
explored the relationship between iron availability and HAPH
Author: Michelle Liu, MPH (No change) Medical Reviewer: Kristen Fuller, MD (No change) Primary Changes: Reviewed entire article and revised where necessary to improve factual accuracy, clarity, and enhanced readability
If it lasts I will be one of the lucky ones
ERdj5, a disulfide reductase in the ER, maintains the redox homeostasis of the ER and combats oxidative stress during aging by receiving electrons from ERO1 and inhibiting the ERO1-dependent production of H 2 O 2 in the ER (Uegaki et al., 2023)
This protective effect is likely mediated through activation of the nuclear factor erythroid 2related factor 2/heme oxygenase-1 (Nrf2/HO-1) signaling pathway (Mao et al., 2024)
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