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Lancet (2021) 398:181124
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These two entities are more common in a Marfan syndrome, which is a disorder of collagen tissue in which the aorta can become quite enlarged and the aortic valve can leak, and the mitral valve can be quite floppy and prolapse significantly and can leak significantly also
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Aging is a diverse and multifaceted process as different organs within an individual undergo distinct aging trajectories influenced by genetic, environmental, and lifestyle factors [78]
