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Glucagon like peptide-1 (GLP-1) is the natural ligand of GLP-1R
As you age the levels of this powerful antioxidant in your body and cells fall and it is further depleted by stress, infection, illness, and exercise
At 24 weeks post-cessation: Tapered group: regained 8.2% of body weight Abrupt cessation group: regained 9.7% of body weight Difference: 1.5 percentage points (not statistically significant, p = 0.18) However, the tapered group reported significantly lower hunger scores in weeks 1 to 4 post-cessation (mean visual analog scale score 6.2 vs 7.8, p = 0.003)
This empowers individualized care tailored to each person's metabolic and health status
Patients using oral contraceptives should be aware that tirzepatide may reduce the effectiveness of these medications, particularly during initiation and dose escalation
Jeffrey Egler
