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Based on direct head-to-head evidence from the SUSTAIN 7 trial, semaglutide produces statistically greater reductions in HbA1c and approximately twice the weight loss compared with dulaglutide at matched dose levels
10% of patients ( n = 16) clearly indicated the medication was being used for weight loss, but indication of prescription was not reported in 38% ( n = 58) of patients
Conclusion The numbers leave little room for ambiguity
But heres something important: you dont need medication to influence GLP-1 levels
A cystatin C above 1.0 mg/L, even within some labs' normal ranges, predicts cardiovascular mortality independently of traditional risk factors
