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These drugs originally developed by companies like Novo Nordisk and Eli Lilly have seen unprecedented demand, leading to shortages and a surge in compounded alternatives from pharmacies

The same pattern was noted across the individual MACE components of CV death, nonfatal MI and nonfatal stroke

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Accordingly, in vitro and ex vivo studies have shown that exposure to saxagliptin (135, 136) but not sitagliptin (136), results in altered cardiac electrophysiology and is associated with impaired cardiomyocyte contractility

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Supporting Clients Through These Questions For many of my clients, conversations about GLP-1s dont come out of nowhere