For TB-500 / thymosin beta-4, the supportive rationale is the well-documented role of thymosin beta-4 in actin regulation, cell migration and wound healing again, largely from cell and animal models rather than human recovery trials
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From that beginning, other researchers began looking for other ways in which the ulcer-healing compound, now called Body Protection Compound 157 (a marketing bonanza for those who would later promote it as a supplement), could be applied to sports injuries, ranging from muscle and tendon tears to cartilage damage, or even stress fractures and fully broken bones
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Faster return to running through effective treatment carries significant practical value for serious runners