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Expected timelines for improvement vary by condition and individual

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The type I IFN pathway is a key point for the start of the vitiligo immune response

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and a multifaceted anti-inflammatory strategy based on pharmacological activation of Nrf2 and enhancement of GSH precursors like bonded cysteine or NAC can be deployed against the virus (Cuadrado et al., 2019

In a transgenic model of hair cell ablation in neonatal mice, Lgr5 -positive cells can, to a limited degree, proliferate and regenerate hair cells after damage (Cox et al., In addition to the mitogenic effect exerted by Wnt/-catenin signaling, studies on cochlear development in both mice and chicken suggest that overexpression of -catenin can induce ectopic hair cell formation (Stevens et al., 2003