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However, he recommends seeing a healthcare professional for the following: Signs of dehydration (e.g., dark and decreased urine, dizziness, dry mouth, rapid pulse, etc.) Severe abdominal pain Persistent vomiting Bottom line: Zepbound diarrhea is typically mild Will you experience diarrhea while taking Zepbound

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In this context, studies in heterozygous Gpx4 knockout mice did not report cell death (or related organ dysfunction) 11,29,48

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Marketed as Mounjaro (for diabetes) and Zepbound (for weight loss), tirzepatide has shown greater weight loss than semaglutide in head-to-head clinical trials

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But tirzepatide may be potentially more effective in achieving weight loss goals, which can outweigh these mild symptoms for many users

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