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It activates both GLP-1 and GIP receptors, making it more effective than earlier single hormone injections
Coadministration of glucagon-like peptide-1 during glucagon infusion in humans results in increased protein synthesis, lipolysis, and energy expenditure
Common side effects include mild nausea, digestive changes, or fatigue, especially early on
However, its clinical application has been limited by dose-dependent gastrointestinal toxicity observed in later phase I and II clinical trials
It sees ethanol as a toxin
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