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Moreover, as illustrated in Figure 15, the binding pattern of SR18 with GLP-1R resembles that of two other reported GLP-1RAs, such as Orforglipron (LY3502970) and peptide 5 (10 aa)
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10.1152/ajpcell.00457.2005 268 SearlesC
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In order to account the variability associated with the flexibility of the loops, here five different loop conformations have been considered in the analysis
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