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Description

Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food

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2016;94(3):e170-176

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McCarty MF, Block KI (2006) Preadministration of high-dose salicylates, suppressors of NF-B activation, may increase the chemosensitivity of many cancers: an example of proapoptotic signal modulation therapy

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This landscape illustrates both the promise and challenges: multiple valid targets exist, but translational failures have been common

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