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Historically, there have been few FDA-approved medications for fatty liver disease, although some drugs used for related conditions showed benefits

Currently, AUD has only three FDA-approved drug treatments: acamprosate disulfiram naltrexone The JAMA Psychiatry study builds on evidence suggesting that GLP-1 drugs could help treat AUD

To be eligible for the trial (ACTG A5371) adults had to be taking antiretroviral therapy that controlled their HIV infection, have a waist circumference at or above 95 cm in men and 94 cm in women, have insulin resistance or prediabetes, and have 5% or higher intrahepatic triglycerides on MRI-PDFF

Combination with metformin has been approved to be safe and is devoid of serious drug interaction when used with glimepiride

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Common ones include: Nausea, diarrhea, constipation, vomiting, and abdominal pain