Here, we examined the effects of ARTHS mutations on histone acetylation in human cells and the effects of heterozygous loss of Kat6a in mice ( Kat6a +/ ) on learning, memory, activity, and sociability
Malhotra A, Grunstein RR, Fietze I, Weaver TE, Redline S, Azarbarzin A
DOI: 10.1001/jamanetworkopen.2025.0802,
(5) Spiering BA, et al
Through systematic variation of receptor potency ratios, the authors identified compounds achieving maximal weight loss and glucose control in obese mice, confirming that receptor balance cannot yet be predicted in silico due to complex receptor crosstalk and feedback regulation
They are particularly well known for their role in building and maintaining muscle , as they provide the essential amino acids the body needs for this