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It is abundant in human tissues, but subject to decline with aging

The opportunity for an oral GLP-1 medication with highly effective weight loss that is simpler to take may provide increased access and opportunities for better health for our patients with obesity and diabetes, said Deborah Horn, DO, MPH, professor and director of obesity medicine at McGovern Medical School at UTHealth Houston and principal author of the study

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Bibcode:2002PNAS...99.2356L

doi:10.1016/j.cmet.2016.02.005 Bartels RD, Kelly KM, Rothman AJ

Muscle growth occurs when the synthesis of muscle proteins surpasses the rate at which muscle tissue breaks down