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Clin Endocrinol (Oxf) 51:787792 Backeljauw PF, Underwood LE (1996) Prolonged treatment with recombinant insulin-like growth factor-1 in children with growth hormone insensitivity syndrome a clinical research center study

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These approaches improve TPP conjugation stability, reduce dissociation and metabolic degradation, and thereby enhance overall targeting efficiency [91]