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This randomized, placebo-controlled, multiple-ascending dose, phase 1b trial aims to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics increasing cagrilintide doses (0.16 4.5 mg) vs

The metabolism of lipids starts with the breakdown of ingested fats into smaller particles by bile, followed by the conversion into free fatty acids and monoglycerides by enzymes from the pancreas and small intestine [19] (Fig

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