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Serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) peaked at 12 h in both mice genotypes (Figures 2a and b)

This assay comprised Flag-ERK5, the 3XMEF2-luc plasmid, and the Renilla luciferase pRL-SV40 reporter vector as a transfection control to normalize luciferase activities

Wegovy comes in single-use pens, while Ozempic pens contain multiple doses

Additionally, ongoing research and development efforts are needed to overcome current limitations and improve the overall safety and tolerability of GLP-1 medications.

Wrbel et al., 2021

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