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Ratner, R

Unresolved questions and future directions Currently, despite promising prospects in preclinical models, targeting glutamine metabolism faces challenges in clinical trials due to inherent heterogeneity in glutamine metabolism within tumor cells and immune cells, as well as its complex impact on immune responses

mouse Bdnf -reverse, 5-CGCTAATACTGTCACACACGC-3

Two-dimensional (2D) structures of the chemical compounds were obtained from PubChem ( Molecular docking simulations were conducted using Schrdinger 2023 software (Schrdinger, New York, NY, USA) ( 2.17 Statistical analysis All statistical analyses were conducted using GraphPad Prism 10 (GraphPad Software, Boston, MA, USA), and results are reported as the mean standard deviation

The cells were treated with 10 mM EtGSH in FluoroBrite DMEM for 34 h or vehicle (FluoroBrite DMEM)

Glutathione plays a crucial role in protecting cells from oxidative stress and supporting overall health